Game 1: Miami Ohio RedHawks

When: Saturday, Sept. 3 at 7 p.m.Location: Kroger Field in Lexington, Kentucky
Series Record: 8-1-4 (Miami last victory in 1979)
Last Meeting: Sept. 7, 2013 (UK won 41-7)
2021 Record: 7-6
Key Player: Junior quarterback Brett Gabbert, brother of NFL quarterback Blaine Gabbert. 2,648 yards, 26 touchdowns and six interceptions in 2021.

Game 2: Florida Gators

When: Saturday, Sept. 10 at 7 p.m.
Location: Ben Hill Griffin Stadium in Gainesville, Florida
Series Record: 19-53 (Longest win streak: 31 for Florida)
Last Meeting: Oct. 2 2021 (UK won 20-13)
2021 Record: 6-7
Key Player: Sophomore running back Montrell Johnson Jr. Transfer from Louisiana, former school of new head coach Billy Napier.

Game 3: Youngstown State Penguins

When: Saturday, Sept. 17
Location: Kroger Field in Lexington, Kentucky
Series Record: 0-0
Last Meeting: N/A
2021 Record: 3-7
Key Player: Senior tailback Jaleel Mclaughlin. Amassed 893 yards on 133 carries, an average of 107.9 yards per contest while scoring 10 touchdowns and caught 20 passes for 175 yards.

Game 4: Northern Illinois Huskies

When: Saturday, Sept. 24 time TBA
Location: Kroger Field in Lexington, Kentucky
Series Record: 0-0
Last Meeting: N/A
2021 Record: 9-5 (MAC Champion)
Key Player: Sophomore running back Harrison Waylee. 574 yards on 101 carries to average 5.7 yards per carry and 114.8 yards per game with four touchdowns in five games before suffering injury.

Game 5: No. 21 Ole Miss Rebels

When: Saturday, Oct. 1 time TBA
Location: Vaught-Hemingway Stadium in Oxford, Mississippi
Series Record: 14-1-28 (Current win streak: two for Ole Miss)
Last Meeting: Oct. 3, 2020 (Ole Miss won 42-41)
2021 Record: 10-3
Key Player: Junior running back Zach Evans. Leads all power-five running backs in yards after contact per attempt (4.8) and led TCU in rushing yards (648) in 2021 despite only playing in six games before transferring to Ole Miss.

Game 6: South Carolina Gamecocks

When: Saturday Oct. 8 time TBA
Location: Kroger Field in Lexington Kentucky
Series Record: 14-1-18 (Longest win streak: 10 for USC)
Last Meeting: Sept. 25, 2021 (UK won 16-10)
2021 Record: 7-6
Key Player: Redshirt junior quarterback Spencer Rattler. 1,438 yards, 11 touchdowns, five interceptions at Oklahoma in 2021. Ranked first in the Big 12 in completion percentage (74.9-percent)

Game 7: Mississippi State Bulldogs

When: Saturday, Oct. 15 time TBA
Location: Kroger Field in Lexington, Kentucky
Series Record: 24-25 (Longest win streak: eight for UK)
Last Meeting: Oct. 30, 2021 (MSU won 31-17)
2021 Record: 7-6
Key Player: Junior quarterback Will Rogers. Led the SEC in passing yards per game in 2021 with 364.5 and his 4,739 total passing yards went into the record books as third most in SEC history.

Game 8: Tennessee Volunteers

When: Saturday, Oct. 29 time TBA
Location: Neyland Stadium in Knoxville, Tennessee
Series Record: 26-9-82 (Largest margin of victory: 52-0 UT in 1994)
Last Meeting: Nov. 6, 2021 (UT won 45-42)
2021 Record: 7-6
Key Player: Redshirt senior quarterback Hendon Hooker. National player of the year candidate for 2022. Racked up 3,561 yards of total offense and set two school single-season records: passer efficiency rating and completion percentage.

Game 9: Missouri Tigers

When: Saturday Nov. 5 time TBA
Location: Faurot Field in Colombia, Missouri
Series Record: 8-4 (Longest win streak: five for UK)
Last Meeting: Sept. 11, 2021 (UK won 35-28)
2021 Record: 6-7
Key Player: Junior defensive back Kris Abrams-Draine. Made three interceptions while breaking up seven passes and had 484 yards from kick returns. Also finished the season with 37 tackles.

Game 10: Vanderbilt Commodores

When: Saturday Nov. 12 time TBA
Location: Kroger Field in Lexington, Kentucky
Series Record: 48-4-42 (Current win streak: six for UK)
Last Meeting: Nov. 13, 2021 (UK won 34-17)
2021 Record: 2-10
Key Player: Fifth year defensive lineman Elijah McAllister. Made 23 tackles with a sack and interception in 2021. Was selected as Mr. Commodore.

Game 11: No. 3 Georgia Bulldogs

When: Saturday, Nov. 19 time TBA
Location: Kroger Field in Lexington, Kentucky
Series Record: 12-2-61 (Current win streak: 12 for UGA)
Last Meeting: Oct. 16, 2021 (UGA won 30-13)
2021 Record: 14-1 (National Champion)
Key Player: Sophomore tight end Brock Bowers. All-American and All-SEC first team member as a freshman with 56 catches for 882 yards and 13 touchdowns.

Game 12: Louisville Cardinals

When: Saturday, Nov. 26 time TBA
Location: Kroger Field in Lexington, Kentucky
Series Record: 18-15 (Current win streak: three for UK)
Last Meeting: Nov. 27, 2021 (UK won 52-21)
2021 Record: 6-7
Key Player: Senior quarterback Malik Cunningham. 2,941 yards, 19 touchdowns, 6 interceptions in 2021.